Publications

ARCAID PUBLICATIONS (Most recent first, click on the blue link to access the paper)

Roet, Janna & Morrison, Andrew & Mikula, Aleksandra & Kok, Michael & Panocha, Daphne & Roest, Henk & Van der Laan, Luc & De Winde, Lotte & Mebius, Reina. (2024). Human lymph node fibroblastic reticular cells maintain heterogeneous characteristics in culture. iScience. 27. 110179. 10.1016/j.isci.2024.110179.

Morrison AI, Sjoerds MJ, Vonk LA, Gibbs S, Koning JJ. In vitro immunity: an overview of immunocompetent organ-on-chip models. Front Immunol. 2024 May 21;15:1373186. doi: 10.3389/fimmu.2024.1373186. PMID: 38835750; PMCID: PMC11148285.

Asal, M., Rep, M., Bontkes, H.J. et al. Towards Full Thickness Small Intestinal Models: Incorporation of Stromal Cells. Tissue Eng Regen Med 21, 369–377 (2024). https://doi.org/10.1007/s13770-023-00600-6

Jiménez-Martínez M, Dankers W, van Baarsen LGM. The key role of the lymph node niche in the development of rheumatoid arthritis. Joint Bone Spine. 2024 Mar;91(2):105661. doi: 10.1016/j.jbspin.2023.105661. Epub 2023 Nov 15. PMID: 37977526.

Morrison AI, Mikula AM, Spiekstra SW, de Kok M, Affandi AJ, Roest HP, van der Laan LJW, de Winde CM, Koning JJ, Gibbs S, Mebius RE. An Organotypic Human Lymph Node Model Reveals the Importance of Fibroblastic Reticular Cells for Dendritic Cell Function. Tissue Eng Regen Med. 2023 Dec 19. doi: 10.1007/s13770-023-00609-x. Epub ahead of print. PMID: 38114886.

Merino-Vico A, van Hamburg JP, Tuijnenburg P, Frazzei G, Al-Soudi A, Bonasia CG, Helder B, Rutgers A, Abdulahad WH, Stegeman CA, Sanders JS, Bergamaschi L, Lyons PA, Bijma T, van Keep L, Wesenhagen K, Jongejan A, Olsson H, de Vries N, Kuijpers TW, Heeringa P, Tas SW. Targeting NF-κB signaling in B cells as a potential new treatment modality for ANCA-associated vasculitis. J Autoimmun. 2024 Jan;142:103133. doi: 10.1016/j.jaut.2023.103133. Epub 2023 Nov 8. PMID: 37931331.CopyDownload .nbib

Parra Sanchez AR, Grimberg MG, Hanssen M, Aben M, Jairth E, Dhoeme P, Tsang-A-Sjoe MWP, Voskuyl A, Jansen HJ, van Vollenhoven R. Web-based eHealth Clinical Decision Support System as a tool for the treat-to-target management of patients with systemic lupus erythematosus: development and initial usability evaluation. BMJ Health Care Inform. 2023 Sep;30(1):e100811. doi: 10.1136/bmjhci-2023-100811. PMID: 37751942; PMCID: PMC10533702.

Parra Sánchez, A.R., van Vollenhoven, R.F., Morand, E.F. et al. Targeting DORIS Remission and LLDAS in SLE: A Review. Rheumatol Ther (2023). https://doi.org/10.1007/s40744-023-00601-w

van den Ende T, Ezdoglian A, Baas LM, Bakker J, Lougheed SM, Harrasser M, Waasdorp C, van Berge Henegouwen MI, Hulshof MCCM, Haj Mohammad N, van Hillegersberg R, Mook S, van der Laken CJ, van Grieken NCT, Derks S, Bijlsma MF, van Laarhoven HWM, de Gruijl TD. Longitudinal immune monitoring of patients with resectable esophageal adenocarcinoma treated with Neoadjuvant PD-L1 checkpoint inhibition. Oncoimmunology. 2023 Jul 17;12(1):2233403. doi: 10.1080/2162402X.2023.2233403. PMID: 37470057; PMCID: PMC10353329.

Chiara E Geyer, Hung-Jen Chen, Alexander P Bye, Xue D Manz, Denise Guerra, Tom G Caniels, Tom PL Bijl, Guillermo R Griffith, Willianne Hoepel, Steven W de Taeye, Jennifer Veth, Alexander PJ Vlaar, Amsterdam UMC COVID-19 Biobank, Gestur Vidarsson, Harm Jan Bogaard, Jurjan Aman, Jonathan M Gibbins, Marit J van Gils, Menno PJ de Winther, Jeroen den Dunnen. 2023 Life Science Alliance Sep 2023, 6 (11) e202302106; DOI: 10.26508/lsa.202302106.  Identification of new drugs to counteract anti-spike IgG-induced hyperinflammation in severe COVID-19 | Life Science Alliance (life-science-alliance.org)

Philippon EML, van Rooijen LJE, Khodadust F, van Hamburg JP, van der Laken CJ and Tas SW (2023) A novel 3D spheroid model of rheumatoid arthritis synovial tissue incorporating fibroblasts, endothelial cells, and macrophages. Front. Immunol. 14:1188835. doi: 10.3389/fimmu.2023.1188835

García-Valiente, R., Merino Tejero, E., Stratigopoulou, M. et al. Understanding repertoire sequencing data through a multiscale computational model of the germinal center. npj Syst Biol Appl 9, 8 (2023). https://doi.org/10.1038/s41540-023-00271-y

Nikolakis, D., Garantziotis, P., Sentis, G. et al. Restoration of aberrant gene expression of monocytes in systemic lupus erythematosus via a combined transcriptome-reversal and network-based drug repurposing strategy. BMC Genomics 24, 207 (2023). https://doi.org/10.1186/s12864-023-09275-8

Rogier C, Frazzei G, Kortekaas MC, Verstappen M, Ohrndorf S, van Mulligen E, van Vollenhoven RF, van Schaardenburg D, de Jong PHP, van der Helm-van Mil AHM. An ultrasound negative for subclinical synovitis in arthralgia patients: is it helpful in identifying those not developing arthritis? Rheumatology (Oxford). 2022 Nov 28;61(12):4892-4897. doi: 10.1093/rheumatology/keac239. PMID: 35416958; PMCID: PMC9707035.

Merino-Vico A, Frazzei G, van Hamburg JP, Tas SW. Targeting B cells and plasma cells in autoimmune diseases: from established treatments to novel therapeutic approaches. Eur J Immunol. 2022 Oct 31. doi: 10.1002/eji.202149675. Epub ahead of print. PMID: 36314264.Targeting B cells and plasma cells in autoimmune diseases: from established treatments to novel therapeutic approaches (wiley.com)

Frazzei G, Musters A, de Vries N, Tas SW, van Vollenhoven RF. Prevention of rheumatoid arthritis: A systematic literature review of preventive strategies in at-risk individuals. Autoimmun Rev. 2022 Oct 21:103217. doi: 10.1016/j.autrev.2022.103217. Epub ahead of print. PMID: 36280095.https://www.sciencedirect.com/science/article/pii/S1568997222001872

Nikolakis, D., de Voogd, F., Pruijt, M. J., Grootjans, J., van de Sande, M. G., & D’Haens, G. R. (2022). The Role of the Lymphatic System in the Pathogenesis and Treatment of Inflammatory Bowel Disease. International journal of molecular sciences, 23(3), 1854. IJMS | Free Full-Text | The Role of the Lymphatic System in the Pathogenesis and Treatment of Inflammatory Bowel Disease (mdpi.com)

Frazzei Giulia, van Vollenhoven Ronald F, de Jong BA, Siegelaar SE and van Schaardenburg D (2022) Preclinical Autoimmune Disease: a Comparison of Rheumatoid Arthritis, Systemic Lupus Erythematosus, Multiple Sclerosis and Type 1 Diabetes. Front. Immunol. 13:899372. doi: 10.3389/fimmu.2022.899372Frontiers | Preclinical Autoimmune Disease: a Comparison of Rheumatoid Arthritis, Systemic Lupus Erythematosus, Multiple Sclerosis and Type 1 Diabetes (frontiersin.org)

The BNT162b2 mRNA SARS-CoV-2 vaccine induces transient afucosylated IgG1 in naive but not antigenexperienced vaccine. Van Coillie J, Pongracz T, Rahmöller J, Chen HJ, Geyer CE, van Vlught LA, Buhre JS , Šuštić T, van Osch TLJ, Steenhuis M, Hoepel W, Wang W, Lixenfeld AS, Nouta J, Keijzer S, Linty F, Visser R, Larsen MD, Martin EL, Künsting I, Lehrian S, von Kopylow V, Kern C, Lunding HB, de Winther M, van Mourik N, Rispens T, Graf T, Slim MA, Minnaar R, Bomers MK, Sikkens JJ, Vlaar APJ, van der Schoot CE, den Dunnen J, Wuhrer M, Ehlers M, Vidarsson G, the Fatebenefratelli-Sacco Infectious Diseases Physicians group and UMC COVID-19 S3/HCW study group. bioRxiv 2022.02.14.480353; The BNT162b2 mRNA SARS-CoV-2 vaccine induces transient afucosylated IgG1 in naive but not antigen-experienced vaccinees | bioRxiv 

Bridging Insights From Lymph Node and Synovium Studies in Early Rheumatoid Arthritis. Aoife M. O’Byrne, Tineke A. de Jong and Lisa G. M. van Baarsen (2022). Front. Med. 8:820232. doi: 10.3389/fmed.2021.820232Frontiers | Bridging Insights From Lymph Node and Synovium Studies in Early Rheumatoid Arthritis (frontiersin.org)

Khodadust F, Ezdoglian A, Steinz MM, van Beijnum JR, Zwezerijnen GJC, Jansen G, Tas SW, van der Laken CJ. Systematic Review: Targeted Molecular Imaging of Angiogenesis and Its Mediators in Rheumatoid Arthritis. International Journal of Molecular Sciences. 2022; 23(13):7071. https://doi.org/10.3390/ijms23137071

Dual Blockade of TNF and IL-17A Inhibits Inflammation and Structural Damage in a Rat Model of Spondyloarthritis Ihsan Hammoura, Renee H. Fiechter, Shaughn H. Bryant, Susan Westmoreland, Gillian Kingsbury, Wendy Waegell, Sander W. Tas, Dominique L. Baeten, Marleen G. H. van de Sande, Melissa N. van Tok and Leonie M. van Duivenvoorde. International Journal of Molecular Sciences. 2022;23(2):859.IJMS | Free Full-Text | Dual Blockade of TNF and IL-17A Inhibits Inflammation and Structural Damage in a Rat Model of Spondyloarthritis | HTML (mdpi.com)

Parra Sánchez, A.R., Voskuyl, A.E. & van Vollenhoven, R.F. Treat-to-target in systemic lupus erythematosus: advancing towards its implementation. Nat Rev Rheumatol 18, 146–157 (2022). https://doi.org/10.1038/s41584-021-00739-3

B Lineage Cells in ANCA-Associated Vasculitis. Ana Merino-Vico, Jan Piet van Hamburg, and Sander W. Tas. Int. J. Mol. Sci. 2022, 23(1), 387; https://doi.org/10.3390/ijms23010387

Steinz MM, Ezdoglian A, Khodadust F, Molthoff CFM, Srinivasarao M, Low PS, Zwezerijnen GJC, Yaqub M, Beaino W, Windhorst AD, Tas SW, Jansen G, van der Laken CJ. Folate Receptor Beta for Macrophage Imaging in Rheumatoid Arthritis. Front Immunol. 2022;13:819163. Published 2022 Feb 2. doi:10.3389/fimmu.2022.819163 PMID: 35185910; PMCID: PMC8849105.

The Role of the Immune System in IBD-Associated Colorectal Cancer: From Pro to Anti-Tumorigenic Mechanisms. Frigerio S, Lartey DA, D’Haens GR, Grootjans J. Int J Mol Sci. 2021 Nov 25;22(23):12739. IJMS | Free Full-Text | The Role of the Immune System in IBD-Associated Colorectal Cancer: From Pro to Anti-Tumorigenic Mechanisms (mdpi.com)

Physiological and Pathological Inflammation Induced by Antibodies and Pentraxins. Chiara Elisabeth Geyer, Lynn Mes, Melissa Newling, Jeroen den Dunnen and Willianne Hoepel. Cells 2021, 10(5), 1175. https://doi.org/10.3390/cells10051175

High titers and low fucosylation of early human anti-SARS-CoV-2 IgG promote inflammation by alveolar macrophages. W. Hoepel et al., Sci. Transl. Med. 10.1126/scitranslmed.abf8654 (2021)High titers and low fucosylation of early human anti–SARS-CoV-2 IgG promote inflammation by alveolar macrophages (science.org)

C-Reactive Protein Controls IL-23 Production by Human Monocytes. Geyer, C.E.; Newling, M.; Sritharan, L.; Griffith, G.R.; Chen, H.-J.; Baeten, D.L.P.; den Dunnen, J. Int. J. Mol. Sci. 2021, 22, 11638.https://doi.org/10.3390/ijms222111638 

Afucosylated IgG characterizes enveloped viral responses and correlates with COVID-19 severity. Larsen MD, de Graaf EL, Sonneveld ME, Plomp HR, Nouta J, Hoepel W, Chen HJ, Linty F, Visser R, Brinkhaus M, Šuštić T, de Taeye SW, Bentlage AEH, Toivonen S, Koeleman CAM, Sainio S, Kootstra NA, Brouwer PJM, Geyer CE, Derksen NIL, Wolbink G, de Winther M, Sanders RW, van Gils MJ, de Bruin S, Vlaar APJ; Amsterdam UMC COVID-19; biobank study group, Rispens T, den Dunnen J, Zaaijer HL, Wuhrer M, Ellen van der Schoot C, Vidarsson G.  Science. 2021 Feb 26;371(6532):eabc8378.doi: 10.1126/science.abc8378.  

Translational Research Studies Unraveling the Origins of Psoriatic Arthritis: Moving Beyond Skin and Joints.  Janne W. Bolt, Chaja M. J. van Ansenwoude, Ihsan Hammoura, Marleen G. van de Sande and Lisa G. M. van Baarsen. Front. Med., 17 August 2021.https://doi.org/10.3389/fmed.2021.711823

IgG Subclasses Shape Cytokine Responses by Human Myeloid Immune Cells through Differential Metabolic Reprogramming. Willianne Hoepel, Sona Allahverdiyeva, Haneen Harbiye,Steven W. de Taeye, Alwin J. van der Ham, Leonie de Boer, Sebastiaan A. J. Zaat, Michel van Weeghel, Dominique L. P. Baeten, Riekelt H. Houtkooper, Bart Everts, Gestur Vidarsson and Jeroen den Dunnen.  The Journal of Immunology, 2020, 205: 000–000. Published November 13, 2020, doi:10.4049/jimmunol.2000263