Dual Blockade of TNF and IL-17A Inhibits Inflammation and Structural Damage in a Rat Model of Spondyloarthritis

Ihsan Hammoura, Renee H. Fiechter, Shaughn H. Bryant, Susan Westmoreland, Gillian Kingsbury, Wendy Waegell, Sander W. Tas, Dominique L. Baeten, Marleen G. H. van de Sande, Melissa N. van Tok and Leonie M. van Duivenvoorde. International Journal of Molecular Sciences. 2022;23(2):859.

IJMS | Free Full-Text | Dual Blockade of TNF and IL-17A Inhibits Inflammation and Structural Damage in a Rat Model of Spondyloarthritis | HTML (mdpi.com)

B Lineage Cells in ANCA-Associated Vasculitis.

Ana Merino-Vico, Jan Piet van Hamburg, and Sander W. Tas. Int. J. Mol. Sci. 2022, 23(1), 387; 

https://doi.org/10.3390/ijms23010387

The Role of the Immune System in IBD-Associated Colorectal Cancer: From Pro to Anti-Tumorigenic Mechanisms.

Frigerio S, Lartey DA, D'Haens GR, Grootjans J. Int J Mol Sci. 2021 Nov 25;22(23):12739. 

IJMS | Free Full-Text | The Role of the Immune System in IBD-Associated Colorectal Cancer: From Pro to Anti-Tumorigenic Mechanisms (mdpi.com)

Physiological and Pathological Inflammation Induced by Antibodies and Pentraxins.

Chiara Elisabeth Geyer, Lynn Mes, Melissa Newling, Jeroen den Dunnen and Willianne Hoepel. Cells 2021, 10(5), 1175. 

https://doi.org/10.3390/cells10051175

High titers and aberrant glycosylation of early phase anti-SARS-CoV-2 IgG promote hyper-inflammation by alveolar macrophages.

W. Hoepel et al., Sci. Transl. Med. 10.1126/scitranslmed.abf8654 (2021)

High titers and low fucosylation of early human anti–SARS-CoV-2 IgG promote inflammation by alveolar macrophages (science.org)

C-Reactive Protein Controls IL-23 Production by Human Monocytes. 

Geyer, C.E.; Newling, M.; Sritharan, L.; Griffith, G.R.; Chen, H.-J.; Baeten, D.L.P.; den Dunnen, J. Int. J. Mol. Sci. 2021, 22, 11638.

https://doi.org/10.3390/ijms222111638 

Afucosylated IgG characterizes enveloped viral responses and correlates with COVID-19 severity. 

Larsen MD, de Graaf EL, Sonneveld ME, Plomp HR, Nouta J, Hoepel W, Chen HJ, Linty F, Visser R, Brinkhaus M, Šuštić T, de Taeye SW, Bentlage AEH, Toivonen S, Koeleman CAM, Sainio S, Kootstra NA, Brouwer PJM, Geyer CE, Derksen NIL, Wolbink G, de Winther M, Sanders RW, van Gils MJ, de Bruin S, Vlaar APJ; Amsterdam UMC COVID-19; biobank study group, Rispens T, den Dunnen J, Zaaijer HL, Wuhrer M, Ellen van der Schoot C, Vidarsson G.  Science. 2021 Feb 26;371(6532):eabc8378.

doi: 10.1126/science.abc8378.  

Translational Research Studies Unraveling the Origins of Psoriatic Arthritis: Moving Beyond Skin and Joints.

Janne W. Bolt, Chaja M. J. van Ansenwoude, Ihsan Hammoura, Marleen G. van de Sande and Lisa G. M. van Baarsen. Front. Med., 17 August 2021.

https://doi.org/10.3389/fmed.2021.711823

Willianne Hoepel, Sona Allahverdiyeva, Haneen Harbiye,Steven W. de Taeye, Alwin J. van der Ham, Leonie de Boer, Sebastiaan A. J. Zaat, Michel van Weeghel, Dominique L. P. Baeten, Riekelt H. Houtkooper, Bart Everts, Gestur Vidarsson and Jeroen den Dunnen.  The Journal of Immunology, 2020, 205: 000–000. Published November 13, 2020, 

doi:10.4049/jimmunol.2000263